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The Turkish practice of inoculation with smallpox itself was, if not first introduced, certainly popularized in high society in Britain by Lady Mary Wortley Montagu, poet, friend of Pope and other writers, and wife of the British Ambassador to the Sublime Porte. Lady Mary had her own child inoculated, and the Hanoverian Royal family (whose ascent to the throne had earlier been facilitated by the smallpox deaths of more immediate heirs) ensured its succession by inoculating two of the Princess of Wales's children, in 1723. The numbers inoculated remained small, however, and medical effort through the eighteenth century was concentrated on reducing the risks and side-effects of the inoculation process. -------------------------------------------------------------------------------- William Douglass, "M.D.," 1691-1752 "A digression concerning the small-pox," in A summary, historical and political, of the first planting, progressive improvements, and present state of the British settlements in North-America Boston: printed; London: reprinted for R. Baldwin, 1775 (vol. II, 408). 2 volumes. Gift of Dr. Robert M. Gibbes to South Carolina College. Douglass documents from personal experience some of the Next page